https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24978 10% for both over-and underdiagnosis were seen in chronic obstructive pulmonary disease, dementia, Parkinson's disease, heart failure, stroke/transient ischemic attack, and acute myocardial infarction. Diabetes was overdiagnosed in <5% of cases. Conclusion: Over-and underdiagnosis are common in older patients. Explanations for overdiagnosis include subjective diagnostic criteria and the use of criteria not validated in older patients. Underdiagnosis was associated with long preclinical phases of disease or lack of sensitive diagnostic criteria. Factors that predispose to misdiagnosis in older patients must be emphasized in education and clinical guidelines.]]> Wed 24 Nov 2021 15:51:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37277 Wed 16 Sep 2020 16:37:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34829 Wed 15 May 2019 14:52:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49646 Wed 14 Jun 2023 18:39:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47192 Wed 13 Mar 2024 19:10:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52433 Wed 11 Oct 2023 14:47:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:2177 Wed 11 Apr 2018 17:19:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30416 Wed 11 Apr 2018 17:10:58 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15678 Wed 11 Apr 2018 16:50:03 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31090 Wed 11 Apr 2018 16:28:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15295 Wed 11 Apr 2018 16:20:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16809 Wed 11 Apr 2018 12:20:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16952 Wed 11 Apr 2018 11:49:10 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30709 p < 0.01). Measures of compliance including serum β-carotene, lycopene and erythrocyte monounsaturated fatty acids were significantly higher in the MedDiet group at three and six months (p < 0.05). Our results indicate that a population of older Australians can adopt a Mediterranean diet over a six month period]]> Wed 11 Apr 2018 11:30:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1355 Wed 11 Apr 2018 11:19:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22883 Wed 11 Apr 2018 11:04:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18744 Wed 11 Apr 2018 10:05:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55097 Wed 10 Apr 2024 08:45:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38812 Wed 09 Feb 2022 16:45:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25029 Wed 06 Apr 2022 14:00:04 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49079 Wed 03 May 2023 16:14:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37683 n = 536) was conducted to explore relationships between the salt taste-related SNP TRPV1-rs8065080 (assessed by Taqman genotyping assay), dietary habits and biomarkers of health. Data were analysed with standard least squares regression modelling and Tukey's HSD post hoc tests. No association was found between the TRPV1-rs8065080 genotype, sodium intake or multiple diet quality indices (assessed by food frequency questionnaire). Sodium-related markers of health including blood pressure and markers of kidney function (urinary creatinine and albumin/creatinine ratio) and general health markers, such as Body Mass Index (BMI), were also not related to TRPV1-rs8065080 genotype. To date, this study is the most comprehensive investigation conducted to determine if the TRPV1-rs8065080 genotype relates to sodium intake and health markers influenced by sodium intake. Although no significant relationships were found, these findings are an important contribution to the limited body of knowledge surround this SNP. In addition to further research across other ages and cultures, the TRPV1-rs8065080 genotype may interact with other ion channels, and so further studies are required to determine if polymorphic variations influence sodium intake, diet and health.]]> Wed 02 Mar 2022 14:24:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19319 55 years) with obstructive airway disease and healthy controls (N=56) underwent inhaler technique assessment, skin allergy testing, venepuncture, fractional exhaled nitric oxide (FENO) and gas diffusion measurement, exercise testing, sputum induction, and questionnaire assessment. They then completed an assessment burden questionnaire across five domains: difficulty, discomfort, pain, symptoms and test duration. Results: Test perception was generally favourable. Induced sputum had the greatest test burden perceived as being more difficult (mean 0.83, P=0.001), associated with more discomfort (mean 1.3, P<0.001), more painful (0.46, P=0.019), longer test duration (0.84, P<0.001) and worsening symptoms (0.55, P=0.001) than the questionnaires. FENO had a more favourable assessment but was assessed to be difficult to perform. Inhaler technique received the most favourable assessment. Conclusions: Older adults hold favourable perceptions to a range of tests that they might encounter in the course of their care for airway disease. The newer tests of sputum induction and FENO have some observed difficulties, in particular sputum induction. The results of this study can inform current practice by including details of the test and its associated adverse effects when conducting the test, as well as providing clear explanations of the utility of tests and how the results might aid in patient care.]]> Tue 26 Jun 2018 11:28:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28807 65 y with MCI were randomized to receive a supplement rich in the long-chain ω-3 PUFAs eicosapentaenoic acid (EPA; 1.67 g EPA + 0.16 g docosahexaenoic acid DHA/d; n = 12) or DHA (1.55 g DHA + 0.40 g EPA/d; n = 12), versus ω-6 PUFA linoleic acid (LA; 2.2 g/d; n = 9) for 6 mo. Results: The intervention did not show an increase in telomere length with treatment and there was a trend toward telomere shortening during the intervention period. Linear mixed modeling produced a robust model although statistically underpowered. Telomere shortening was greatest in the LA group (d = 0.21) than in the DHA (d = 0.12) and EPA groups (d = 0.06). Increased erythrocyte DHA levels were associated with reduced telomere shortening (r = −0.67; P = 0.02) in the DHA group. Conclusion: Telomeric shortening may be attenuated by ω-3 PUFA supplementation, requiring further investigation in larger samples.]]> Tue 16 Jan 2024 16:02:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43173 Tue 13 Sep 2022 16:03:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38924 Tue 08 Mar 2022 11:01:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51432 Tue 05 Sep 2023 17:57:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30655 Tue 03 Sep 2019 18:30:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29920 Tue 01 May 2018 09:09:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37424 Thu 12 Nov 2020 18:13:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42951 KCNJ2 gene involved in the transduction of sour taste have been linked to variations in sour taste and non-gustatory functions. However, relationships between sour taste genetics, mild cognitive impairment, and diet quality are yet to be elucidated. This study investigated the associations between the presence of the KCNJ2-rs236514 variant (A) allele, diet quality indices, and mild cognitive impairment evaluated by the Mini-Mental State Examination (MMSE), in a secondary cross-sectional analysis of data from the Retirement Health & Lifestyle Study. Data from 524 elderly Australians (≥65y) were analyzed, using standard least squares regression and nominal logistic regression modeling, with demographic adjustments applied. Results showed that the presence of the KCNJ2-A allele is associated with increased proportions of participants scoring in the range indicative of mild or more severe cognitive impairment (MMSE score of ≤26) in the total cohort, and males. These associations remained statistically significant after adjusting for age, sex, and diet quality indices. The absence of association between the KCNJ2-A allele and cognitive impairment in women may be related to their higher diet quality scores in all indices. The potential link between sour taste genotype and cognitive impairment scores may be due to both oral and extra-oral functions of sour taste receptors. Further studies are required on the role and relationship of neurotransmitters, sour taste genotypes and sour taste receptors in the brain, and dietary implications, to identify potential risk groups or avenues for therapeutic or prophylactic interventions.]]> Thu 08 Sep 2022 14:04:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31149 Sat 24 Mar 2018 08:43:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7331 Sat 24 Mar 2018 08:35:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1624 0.05). Conclusions: Malnutrition is common in elderly patients who are nursed at home for wound management. Provision of energy- and protein-dense oral supplements by community nurses is effective in improving some indices of wound healing and cognitive function in this group. Although further study is needed to determine the effect on length of stay, the nutritional needs of this vulnerable group should not be overlooked.]]> Sat 24 Mar 2018 08:30:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10408 Sat 24 Mar 2018 08:07:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18918 Sat 24 Mar 2018 08:03:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17917 55 years) (n = 100) with an OAD underwent a multidimensional assessment (MDA) involving questionnaires, clinical assessments, physiological measurements and biomarkers. Results: the assessment identified a mean (SD) of 11.3 (2.5) clinical management issues and 3.1 (1.8) comorbid conditions per participant. Common problems were: airways hyper-responsiveness (80%); airway inflammation (74%); activity limitation (74%) and systemic inflammation (60.5%). The number and type of issues were similar irrespective of a diagnosis of asthma or COPD (P = 0.2). The degree of health status impairment correlated significantly with the number of clinical management issues detected (r = 0.59; P < 0.0001). Conclusions: older people with OAD experience multiple clinical issues that adversely impact their health status. The number and type are similar irrespective of diagnosis. This MDA identifies significant clinical issues that may not be addressed in a diagnosis centred approach suggesting that a multidisciplinary approach is necessary when assessing and managing older people with OAD.]]> Sat 24 Mar 2018 07:56:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18365 Sat 24 Mar 2018 07:52:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21468 N = 104) were randomly assigned to the experimental or control group. The experimental group received 12 sessions of group music therapy (two 30-min sessions per week for 6 weeks), and the control group received usual care. Data were collected 4 times: (1) 1 week before the intervention. ; (2) the 6th session of the intervention. ; (3) the 12th session of the intervention. ; (4) 1 month after the final session. Results: Group music therapy reduced depression in persons with dementia. Improvements in depression occurred immediately after music therapy and were apparent throughout the course of therapy. The cortisol level did not significantly decrease after the group music therapy. Cognitive function significantly improved slightly at the 6th session, the 12th session, and 1 month after the sessions ended; in particular, short-term recall function improved. The group music therapy intervention had the greatest impact in subjects with mild and moderate dementia. Conclusion: The group music intervention is a noninvasive and inexpensive therapy that appeared to reduce elders’ depression. It also delayed the deterioration of cognitive functions, particularly short-term recall function. Group music therapy may be an appropriate intervention among elderly persons with mild and moderate dementia.]]> Sat 24 Mar 2018 07:52:31 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19181 Sat 24 Mar 2018 07:52:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19368 Sat 24 Mar 2018 07:52:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5007 Sat 24 Mar 2018 07:44:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:189 0.05). Conclusions: Malnutrition is common in elderly patients who are nursed at home for wound management. Provision of energy- and protein-dense oral supplements by community nurses is effective in improving some indices of wound healing and cognitive function in this group. Although further study is needed to determine the effect on length of stay, the nutritional needs of this vulnerable group should not be overlooked. (c) 2005 Elsevier Inc. All rights reserved.]]> Sat 24 Mar 2018 07:42:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27835 Sat 24 Mar 2018 07:41:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27863 Sat 24 Mar 2018 07:41:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26644 Sat 24 Mar 2018 07:26:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30225 Sat 24 Mar 2018 07:26:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3819 Sat 24 Mar 2018 07:22:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52497 Mon 16 Oct 2023 15:10:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52278 Mon 09 Oct 2023 10:02:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51943 Fri 22 Sep 2023 16:57:08 AEST ]]>